Top research doctors at four Southeast Michigan health systems and Wayne State University have formed a partnership to participate in large-scale COVID-19 drug trials they hope will lead to a vaccine, antiviral medicines and other drugs to combat the deadly coronavirus. Physician participants who formed the study group are part of Henry Ford Health System, Ascension Michigan, Beaumont Health, Detroit Medical Center and Wayne State. "We hope our work here will last well into the future, should COVID-19 continue to be a threat," said Dr. Phillip Levy, professor and associate chair for research in Wayne’s State’s department of emergency medicine. "By combining forces, we can marshal greater research capabilities to effectively test vaccines and treatments to combat this virus."

Nearly 3.3 million people are out of work in the United States, according to the most recent jobs report from the U.S. Department of Labor; quadrupling the previous record set in 1982. "These numbers are unprecedented. 3.3 million jobless claims. I think the high water mark in the 80s was 600,000. No one saw this coming," said Matthew Roling, executive director of Wayne State's Office of Business Innovation. And in Michigan, unemployment claims are also way up. There's been a 550 percent increase in the number of claims filed compared to those usually filed during this time of year, according to the Michigan Unemployment Insurance Agency. "And I think it speaks to the total lack of clarity that most employers feel right now," Roling said. He added that small businesses in the state have been hit especially hard under the "Stay Home, Stay Safe" executive order. “Employers don’t really have the freedom or flexibility with their balance sheets the money that they have available, to keep these employees on. And so the most humane thing for them to do is to let these folks go so that they can seek benefits," he said. But Roling also pointed out that Detroit's automakers shifting gears during this crisis, to help make vital medical equipment, is moving Michigan in the right direction in the both the short and long-term. “While obviously making ventilators might not employ the same number of people as making pick-up trucks, a lot of Michigan’s economy is based manufacturing," he said, noting that industry tends.

As the coronavirus advances, it is taking a particularly harsh toll on the many who are caring for a loved one with dementia or Alzheimer’s, the most common form of dementia. While the disease itself does not necessarily place patients at high risk for contracting the virus, they and their caregivers face a range of special challenges. Dementia patients are typically very sensitive to changes in routine and often require a great deal of hands-on care, both factors that are hard to manage now. Family members who usually rely on day care programs or visiting caregivers may be finding themselves with full-time responsibilities, while others whose loved ones are in facilities are unable to visit them now. Among the greatest challenges is how to minimize disruption in care that is intensely personal. “Care for dementia patients is ‘high touch,’” said Peter Lichtenberg, a professor of psychology and director of the Institute of Gerontology at Wayne State University. He recommends that caregivers take measures to avoid their own exposures by having provisions delivered, disinfecting surfaces and employing proper hand-washing techniques

Metro Detroit has become one of the nation’s COVID-19 hotspots. And experts predict the situation will get even more dire in the next several weeks. The city of Detroit is a hotspot within the hotspot. As of Thursday, the city reported 888 COVID-19 cases, with 19 deaths so far. Why is that? Jonathan Stillo, a medical anthropologist and assistant professor at Wayne State University, said some of the explanation for Detroit’s numbers in particular comes down to simple geography—densely-populated urban centers foster the spread of communicable diseases, and Detroit may just be a bit ahead of the curve compared to some other places. “But we’re still nowhere near where we need to be in terms of seeing the whole picture,” Stillo said. “Right now, we’re only seeing little snapshots, and those are totally dependent on how much testing is happening. “It makes the job of researchers, and folks who are trying to figure out what’s going on and make policy to address it, really hard. We’re flying blind, I think, in a lot of ways.” Stillo said data on racial demographics would be helpful. So would data about whether groups of people who are disproportionately sick and dying have certain underlying conditions. Although it’s difficult to tell whether specific racial groups such as African Americans might be at higher risk from COVID-19, Stillo said some basic public health and social science data tell us that’s probably the case. “African American folks in Detroit have higher rates of asthma, they have higher rates of diabetes, they have higher rates of some of these conditions that we think may make outcomes worse,” Stillo said. “You’re sort of layering biological problems on top of already-existing social problems.

Arash Javanbakht, M.D., director of the Stress, Trauma, and Anxiety Research Clinic (STARC) at Wayne State University, wrote a piece for Psychology Today about surviving in the age of COVID-19. Javanbakht wrote: “There are aspects of all of our lives that are affected by the new pandemic, regardless of our political, religious, age, or national background. This virus is a reminder that we humans are all vulnerable to what nature throws at us, and in it together. Overnight, our ability to dine out, be at a coffee shop, or exercise declined. This is important especially for those who had routines including these activities, or those with less social support, whose social interactions were limited to such activities, or their social life did involve such activities like spending time with friends at the gym. Remote working, reduced work hours and income, and inability to predict future of work, especially for those with limited financial resources, or jobs mainly affected by the crisis are highly stressful. We all are also stressed by the news, especially given the inherent emotionally triggering nature of the U.S. news media, and too much focus on disaster pornography, as well as contradicting news, predictions, and recommendations coming from different outlets and authorities. The constantly changing and evolving nature of such news is also stressing on all those who follow them.”

Health care workers and first responders in Detroit and Dearborn with symptoms of COVID-19 can get a free virus screening Sunday. The Wayne State University Physician Group is partnering with  WSU Health Sciences and social service organization ACCESS to provide drive-thru screening from noon to 5 p.m. Sunday at ACCESS Community Health and Research Center in Dearborn. Volunteer clinicians are providing nasal tests at no charge to health care workers, police officers, firefighters, and medics from across the region who are displaying COVID-19  symptoms including fever, cough, shortness of breath, or sore throat. “Wayne State has long played an integral role in the health and well-being of the Detroit community, which is why it’s critical we step up and help test those who are involved in caring for others,” said Wayne State University President M. Roy Wilson. “Testing is an important measure toward controlling the spread of the virus, and we’ve made this drive-through testing process as accessible as possible for those on the front lines of care who have symptoms suggesting that they may be infected.” 

Dr. Paul Kilgore, associate professor and director of research at Wayne State’s Eugene Applebaum College of Pharmacy and Health Sciences, talked about the medical and public safety implications of the novel coronavirus on Detroit Today with Stephen Henderson. What are requirements for getting a test? “You can list, write down signs and symptoms you’re experiencing, including when they started. Record if symptoms getting worse. Call doctor/nurse and they’ll tell you if you need a test,” said Kilgore. At what point should people consult their doctor if they think they have symptoms? “The “disease can progress fairly rapidly, [so] write down progression. [It] doesn’t hurt to call the clinic if you have signs/symptoms and let them know, better early than late.” How do we help elders in our neighborhood or in our family in a safe way? “Organizations are out there trying to help, but don’t always know where vulnerable populations are. Might help to let those organizations know where help is needed.”

Some local groceries have been picked thin in the wake of thousands of Metro Detroiters stocking up in preparation for quarantine. But instead of frozen and canned foods, one Wayne State nutritionist says creating your own soups and grain-based dishes is a healthier way to feed yourself and your family during this crisis. “You don’t want to be throwing anything away right now. You want to maximize what you have,” said Wayne State University nutritionist Diane Cress. Cress says, before you go shopping again, pay attention to what can still be used at home. “Get your nutrients from food and then you get the right doses. If you get them from supplements, things are imbalanced. Food is cheaper and tastes better.”

Wayne State University has postponed spring commencements amid the coronavirus (COVID-19) scare. As Michigan government officials increase measures to enforce social distancing, WSU officials say they had to postpone the event due to the large crowds that attend. “We understand that commencement is an important milestone, one worthy of the traditional pomp and circumstance,” said Provost and Senior Vice President for Academic Affairs Keith Whitfield. “You have worked long hours to earn a degree and we, like you, looked forward to celebrating this day with you and your family and friends. Know that this news [is] as disappointing to us as it is you.” Students that have met their requirements will still receive their degrees, however, according to officials. WSU students can learn more about how COVID-19 affects them here

Who is incarcerated in Michigan’s county jails, their length of sentence, and how many die there is unknown — and it has been that way for decades. Policymakers say they're taking steps to fix this broken system, but with little data to go by, responding to the mental health needs of those in county jails is like working in the dark. Sheryl Kubiak, dean of Wayne State’s School of Social Work, has spent her career researching the intersection of criminal justice and heath care. She served on the Task Force with Lt. Gov. Garlin Gilchrist and State Supreme Court Chief Justice Bridget McCormack. Improving outcomes for inmates, connecting them with services and giving corrections officers the information they need requires an intake system that asks the right questions, Kubiak said. There are a variety of jail management software programs available to purchase, with little uniformity from county to county, Kubiak said. The software is expensive and takes training to learn how to use, making it difficult for jail administrators to justify changing even if their current system is not as effective as they’d like. “In the best case scenario, there would be a uniform system that all the jails would use,” Kubiak said, in a telephone interview. “But to require that, the state would have to fund it. And that would be a big ticket item.” Some jails, such as Kalamazoo County, are paper and pencil, Kubiak said, with no jail management information software at all. Nor is there a robust oversight mechanism to make sure county jails are operating as they should.

A late February study in the Journal of the American Medical Association showed that children 10 and under accounted for just 1% of all COVID-19 cases, for example, while adults in the 30-79 age groups represented a whopping 87%. The World Health Organization (WHO) found something similar in China, with 78% of patients falling between the ages of 30 and 69. “Older people are more likely to be infected, especially older people with underlying lung disease,” says Dr. Teena Chopra, medical director of infection prevention and hospital epidemiology at Wayne State University. “For this population, mortality rates for COVID-19 are about 15%.” In this sense, COVID-19 behaves a lot like seasonal flu. From 70% to 85% of all flu deaths and 50% to 70% of flu-related hospitalizations occur among people in the 65-plus age group, according to the United States Centers for Disease Control and Prevention (CDC). The 2002-2003 SARS outbreak similarly proved lethal for more than 50% of people over 60 who contracted the disease. “People living in long care facilities have common meetings, they share common rooms,” says Chopra. Common meetings and common rooms can too often mean common pathogens. The health system itself may be playing a significant role in putting seniors at risk. People with multiple medical conditions typically visit multiple specialists, and every such visit means entering a health care environment that can be teeming with viruses and bacteria. For now, Chopra advises older patients to postpone doctor visits that aren’t absolutely essential, like “their annual eye visit. Dental cleaning can be avoided too.” Telemedicine—conducting doctor visits that don’t require hands-on treatment online—can be helpful too, as can e-prescribing, with drugs being delivered straight to patients, sparing them exposure to pharmacies.

At a campaign rally this week in North Carolina, President Trump reassured the crowd that he had jawboned the nation’s pharmaceutical companies into quickly tackling the coronavirus. “They’re going to have vaccines, I think, relatively soon,” he said. But “soon” was correct only if it meant 12 to 18 months from now. Both health officials and drug industry executives have repeatedly told Trump that a vaccine was still a long way off. Yet by promising a vaccine “soon,” the president almost certainly misled at least some of the public into thinking a solution to the outbreak was just around the corner. In confronting the first major health crisis of his presidency, Trump has made himself the primary source of information to the public with mixed results. Appearing before cameras sometimes multiple times a day to talk about the coronavirus, he has offered a consistently rosier assessment of the situation than health experts and has put forth unproven or even false assertions. “I think it’s fair to say that President Trump has struggled, and that’s not surprising,” said Matthew Seeger, a dean at Wayne State University who has written extensively on crisis communications. “One of the real challenges we’ve seen is a tendency to over-reassure. There is a tendency for us to say, ‘Don’t worry, everything is going to be fine, don’t panic.’”

Learn the secrets of some of the most mysterious phenomena in space this Thursday, February 27, at Hopcat in Detroit. Wayne State Astrophysicist Ed Cackett will help you explore the university’s latest research on the physics of black holes and neutron stars, both some of the most compact objects in the universe. Neutron stars, for example, says Cackett, are some of the densest. “The material inside [a neutron star] is denser than an atomic nucleus. The equivalent is crushing down the entirety of humanity into the size of a sugar cube.” Cackett also studies black holes, one of the most misunderstood physical phenomena in popular culture. He says, with Wayne State’s Dan Zowada Memorial Observatory in New Mexico, he and other researchers can look at how objects fall into black holes, specifically, by measuring the light that’s emitted as they fall past the event horizon.

Randall Commissaris, a Wayne State University associate professor of pharmaceutical sciences, is studying the effects of using marijuana or alcohol when driving vehicles. Wayne State has several research projects underway, including the one by Commissaris, who runs a driving safety lab in the college of pharmacy and is studying the reaction time of people under the influence of marijuana or alcohol. Commissaris said the driving simulation places subjects in a 2001 Chevy Impala and presents a road filled with obstacles to drive around. "We collect data in a flight data-type recorder and look at driving performance using cannabis and while drinking," he said. "We worked with medical marijuana patients for two years, but in December 2018 when recreational became legal we started working with them." Under the influence or marijuana or alcohol, the reaction time is longer, but much of it depends with how much is consumed and their tolerance level. "We are still studying everything, but we are seeing a greater tolerance level with marijuana than alcohol," he said. "If the subject has a history with marijuana they are less affected in the driving test. There is a little evidence of that with alcohol but more with marijuana." Commissaris said Wayne State is planning to begin studies on edible cannabis products. "There is not enough research on cannabis," he said. "We want to do more, but it is complicated because the products and plants are highly variable in concentration." Another study is being conducted by Christine Rabinak, an associate professor in the WSU pharmacy college, who is conducting a study on the use of cannabis on (post-traumatic stress disorder) patients.

Anne P. DePrince, professor of psychology at the University of Denver, and Jennifer M. Gómez, Wayne State University assistant professor, wrote a Conversation piece about the trial of media mogul Harvey Weinstein and the painful effects on women and minorities. “For months, he (Weinstein) has presented his pain to us, granting a hospital-room interview to catalog his suffering and using a walker on his way in and out of the courthouse. His defense team has argued he deserves your sympathy. They asked the judge to let Weinstein’s surgeon testify to confirm their client is “hurt and enfeebled. These requests for your compassion are reminders that sympathy is not automatic. Not everyone gets our sympathy when they show us their pain. Whose pain, then, are we most likely to see, believe and ultimately award our sympathy? And what do those tendencies mean for health outcomes and courtroom justice? As trauma psychologists, we have spent a great deal of time researching the impact of violence and how survivors are treated when they disclose. In studying trauma and intimate violence, we have learned much about whose pain is believed or disbelieved. Studies suggest there is bias against women and ethnic minorities in both the health care and criminal justice systems. Pain bias in the health care system.”

Michigan Secretary of State Jocelyn Benson is urging businesses to give their workers the day off on Election Day by making it a company holiday. Benson said she’s encouraging Michigan companies to give employees the day off work on Nov. 3, so they can vote and work as poll workers. She praised Wayne State University for recently announcing such a move, MLive.com reported. Keith E. Whitfield, Wayne State’s provost and senior vice president for academic affairs, said that Nov. 3 will be a university holiday, with no classes held and only essential employees reporting to work. “We hope that faculty, staff and students will take advantage of the Election Day holiday to exercise their civic duty and participate in these important national elections,” Whitfield wrote.

Medical trainees want to help in less-resourced countries. But short-term programs can misread local needs, overburden hosts, and send students into situations they're not prepared to handle. Here’s how leaders are ensuring ethical, effective experiences. Programs that want to provide effective, ethical experiences should avoid veering toward "volun-tourism," experts say. Instead, they should build solid, respectful partnerships with local communities. Some call this “fair trade education,” borrowing from the “fair trade” concept that promotes equity between producers, who are often from lower-income places, and consumers in higher-income nations. To make sure it was achieving this and other goals, Wayne State University School of Medicine paused its student-run global health trips a few months ago. Until then, the school’s World Health Student Organization would raise funds, buy medicines, and travel to sites in less-resourced countries. “The students would create pop-up clinics” and organize trips with the help of U.S. nongovernmental organizations, explains Ijeoma Opara, MD, who codirects Wayne State’s new interdisciplinary Global Health Alliance (GHA). “It was students’ responsibility to arrange faculty to accompany them on travel as well as faculty in the host country to provide oversight.” Now, though, the school is working on extensive changes. “We want to focus on structured, competency-based learning experiences as well as on developing strong, long-term, bidirectional relationships with faculty leadership in host countries,” says Opara. “Hosts should be fully engaged in program design and defining intended outcomes. Only they really know their resources, their needs, and their capacity." At Wayne State, predeparture trainings include lessons in the history, language, and culture of destinations, combined with modules from the University of Minnesota’s Global Ambassadors for Patient Safety program. Students’ failure to understand local values can inadvertently cause problems for both patients and providers, notes Kristiana Kaufmann, M.D., who codirects the school’s GHA program with Opara.

Wayne State University has established a polling location to serve Detroit's Precinct 149, a little over a month before the presidential primary election March 10. All voters of Precinct 149 will now cast ballots at the university's polling location inside the Wayne State Law School, 471 West Palmer. Secretary of State Jocelyn Benson joined university officials and Detroit City Clerk Janice Winfrey for the announcement Wednesday afternoon at the Damon J. Keith Center for Civil Rights. In November, Wayne State University was recognized for student voting engagement, with a student rate of over 50 percent, earning the university a platinum seal — one of 61 institutions in the country to do so. Student voting at Wayne State increased to 53 percent in 2018 following the midterm elections, up from 27 percent in 2013, while the national average institutional voting rate was 39 percent in 2018, according to the National Study of Learning, Voting, and Engagement. The university Board of Governors also declared Election Day in November a campus holiday, canceling classes and making it easier for students, staff, and faculty to hit the polls. “The university has gone to considerable measures to ensure every student’s voice is heard,” Wayne State University President M. Roy Wilson said. “This student-led initiative celebrates the life and legacy of Judge Damon Keith by making voting and civic engagement more accessible to campus residents. I believe (Keith) would be delighted with today’s announcement.”

Heather E. Mooney, Ph.D. Candidate in Sociology at Wayne State University, wrote an article for The Conversation regarding the effectiveness of private programs designed for troubled teens. “The troubled teen industry is a mostly unregulated collection of for-profit programs that claim to rehabilitate out-of-control youth. Between 50,000 and 100,000 adolescents currently spend at least part of the year in these facilities. Their enrollment – or confinement, depending on the arrangement or their perspective – can prevent these relatively privileged kids from joining the 48,000 youth caught in the U.S. juvenile justice system. With little academic research about these private programs serving troubled teens, the conversation around them strikes me as either overly positive or negative. I’m skeptical about the positive research because most of it has been conducted and funded by the schools themselves or the organizations representing them. These studies also tend to look at limited time frames, such as two years or less after participants have left a “troubled teens” program.”

Tracie Baker wasn’t sure what tools she would need for the dissection. Baker, an environmental toxicologist at Wayne State University, studies the presence and effects of toxins and endocrine-disrupting compounds in water. She’d cut up fish before, but never anything quite like the tangled mess of fats, oils, grease, and trash that had arrived in her lab. It was two 10-pound chunks of fatberg, taken from a massive sewer-clogging bolus. Baker figured she’d need gloves, probably the thick rubber kind people use for washing dishes, and elbow-length seemed safest. Beyond that, she says, “We weren’t exactly sure what was going to work.” Baker and her colleagues were trying to learn as much as they could about the fatberg, which had been hauled from a sewer in Clinton Township, a suburban Michigan community about 25 miles northeast of Detroit in Macomb County, while it was still fetid and fairly fresh. When they were done, it would be enshrined in a new exhibit at the Michigan Science Center. Pieces of the fatberg were worth keeping around for analysis because “so few fatbergs have been characterized,” Baker says. With the exception of a handful extracted in London, studied with gas chromatography or forensically prodded in front of television cameras, the usual approach to them is, “Let’s get this out of here, throw it in the trash, and move on,” Baker says. Along with her Wayne State colleague Carol Miller, a civil and environmental engineer, Baker applied for National Science Foundation funding to take a closer look at the Macomb County fatberg. The team wanted to know exactly what the mess was made of and how it might affect the ecosystem both inside and outside of the sewer.