Two faculty members of the Wayne State University School of Medicine are editors of a new book written to provide clinical sleep medicine practitioners and trainees a collection of chapters examining ventilatory control of breathing while bridging the gap between straightforward physiology and clinical practice.

Professor of Medicine, Associate Chief of Staff, Research and Development Service and Sleep Medicine Section Chief Susmita Chowdhuri, M.D., M.S., and Professor and Chair of Internal Medicine M. Safwan Badr, M.D., M.B.A., along with former WSU Professor of Internal Medicine James Rowley, M.D., are the editors of “Control of Breathing During Sleep: From Bench to Bedside,” by CRC Press, which describes control of ventilation during sleep in both health and disease states.

The book’s contributing writers include experts from North America, Europe and Australia.

Topics include the site of normal respiratory rhythm generation to chemoreceptor control of sleep apnea; description of the apneic threshold pathophysiology of upper airway closure; novel techniques to measure control of breathing; effect of cerebral blood flow on breathing; effect of opioids on ventilation; effect of heart failure on ventilation; genetic aspects of breathing disorders, age and gender differences; and various therapies.

The book also explores various aspects of clinical management and control beneficial to sleep clinicians, respiratory physiologists, intensivists, trainees and researchers; and distills complex concepts into understandable language and figures, providing a helpful and easily understandable resource for clinicians.