A major new pediatric research study led by a Wayne State University researcher has "major implications" for the treatment of urinary tract infections(UTIs) in millions of American children. The largest study of its kind in the world, it provides convincing evidence that children with a common urinary-tract abnormality known as "vesicoureteral reflux" (or "VUR") experience a significantly reduced risk of developing frequent UTIs when treated with long-term low-dose antibiotics. "This newly published study has major implications for the management of UTIs in children," said Tej Mattoo, professor of pediatrics at Wayne State University's School of Medicine and chief of Pediatric Nephrology and Hypertension at the Children's Hospital of Michigan at the DMC. "Our clinical trial analyzed pediatric research data collected during 6 years at 19 different sites in the United States, and what we found was that children with VUR who received antibiotics long-term were 50 percent less likely to develop recurrent UTIs."

http://www.news-medical.net/news/20140508/Research-may-have-major-implications-for-treatment-of-urinary-tract-infections-in-children.aspx
http://groundreport.com/breakthrough-nih-study-by-the-childrens-hospital-of-michigan-nephrology-researcher-will-have-major-implications-for-treating-pediatric-utis/
http://www.asianhhm.com/news/news_archives.asp?NewsID=71679&title=Breakthrough-NIH-Study-by-the-Childrens-Hospital-of-Michigan-Nephrology-Researcher-Will-Have-Major-Implications-for-Treating-Pediatric-UTIs