Working with researchers at Wayne State University, scientists at the Wisconsin-based Paul P. Carbone Comprehensive Cancer Center have discovered a specific biochemical pathway by which androgen - the sex hormone - increases levels of harmful chemicals known as reactive oxygen species (ROS) in the prostate gland that play a role in the development of prostate cancer. The scientists have synthesized a molecule that can block androgen-induced ROS production in prostate cancer cells. More lab tests need to be carried out, but researchers hope clinical trials can begin in 12-18 months.