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New personalized therapy causes cancer cells to kill themselves
An article highlights the research of Dr. Karlie Rosner, assistant professor at Wayne State University's School of Medicine, who developed a concept that successfully uses genetic constructs that contain a genetically modified enzyme - DNase1 protein - to seek out and destroy cancer cells. The novel technology was published in the article \"Engineering a waste management enzyme to overcome cancer resistance to apoptosis: adding DNase1 to the anti-cancer toolbox\" in the Jan. 14 online edition of Cancer Gene Therapy. The beauty of this therapy is that specifically-targeted cancer cells destroy themselves through the physiological mechanism of apoptosis, leaving surrounding healthy cells intact.