School of Medicine in the news

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The science of fright: Why we love to be scared

Whether we love or hate to experience fear, it’s hard to deny that we certainly revere it – devoting an entire holiday to the celebration of fear..All fun aside, abnormal levels of fear and anxiety can lead to significant distress and dysfunction and limit a person’s ability for success and joy of life. Nearly one in four people experiences a form of anxiety disorder during their lives, and nearly 8 percent experience post-traumatic stress disorder (PTSD).
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Wayne State receives $2 million NIH grant for new study on fetal alcohol spectrum disorders

The National Institute of Alcohol Abuse and Alcoholism of the National Institutes of Health has awarded Wayne State University $2,063,188 for a new study that will analyze longitudinal data spanning 20 years collected from five U.S. cohorts, including 480 African-American mothers and children in the Detroit Longitudinal Cohort Study, to take a closer look at the key developmental outcomes and prenatal alcohol exposure levels that characterize FASD.
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New methods make genetic testing simpler and faster

September is Tay-Sachs Awareness Month, highlighting a genetic disorder much more prevalent in the Jewish community than in the population at large. Concern about Tay-Sachs led to interest in screening for Jewish genetic diseases in the 1970s. Since then, the incidence of Tay-Sachs disease, which is invariably fatal, has fallen by more than 90 percent because of genetic screening. Jerry Feldman, M.D., a professor at Wayne State University School of Medicine and director of its Clinical Genetic Services, says the number of identified disorders more common in the Ashkenazi Jewish community has grown to more than 80, but he notes that beyond that, different labs may test for additional mutations that are found in many ethnic groups. 

Psychiatry’s Dr. David Rosenberg talks child and adolescent internet addiction on TV’s ‘20/20’

ABC television and “20/20” program co-anchor Elizabeth Vargas turned to Wayne State University School of Medicine Department of Psychiatry and Behavioral Neurosciences Professor and Chair David Rosenberg, M.D., for insight into the effects of compulsive internet device use on the child and adolescent brain for an episode expected to air May 19 at 10 p.m. Eastern Standard Time. Compulsive internet use is increasingly common, he said. “Internet addiction in children and adolescents is a growing problem and part of our culture. The internet is a wonderful servant, but a cruel and crippling master,” Rosenberg said. “There is some debate in the field about whether internet addiction is real addiction or pathology. We contend it exists, and it can devastate children and their families. But there are differences – as well as similarities – with other addictive behavior, and you can't just stop with a diagnosis of internet addiction, since there are always underlying conditions that must be aggressively diagnosed and treated for the long-term benefit of the internet addiction.” Rosenberg shared with Vargas his department’s approach to internet addiction, brain imaging and neuropsychiatric assessments, as well as problems with executive function, brain abnormalities and changes observed in the brain after digital fasts. A digital fast, also known as a digital detox or unplugging, is when an individual voluntarily stops using all connected devices such as smart phones, tablets and computers for a specific period of time. The department’s preliminary studies, while needing considerable additional research, suggest that brain abnormalities may normalize with a digital fast, but those normalizations may not persist if the individual’s environment does not change. This includes the continuation of possible family behaviors that may enable internet excess. “It is not an isolated phenomenon. There are always associated and underlying conditions, such as depression, poor self-esteem, poor impulse control, anxiety, obsessive compulsive behaviors and chronic pain,” he said. The studies discussed for the television show are facilitated by the unique and state-of-the-art MRI infrastructure at Wayne State University, and the expertise of internationally-recognized scientists and MRI experts Vaibhav Diwadkar, Ph.D., and Jeffrey Stanley, Ph.D., department faculty members who are conducting pioneering and sophisticated MRI imaging studies that are unlocking potential mechanisms for a wide variety of neuropsychiatric disorders. “They are leaders who are sought out by teams doing neuroimaging throughout the United States, and internationally,” Rosenberg said. Filming of clinical interviews and neuropsychiatric/neuropsychologic assessments took place over the last year at WSU’s Tolan Park Medical Office Building and the WSU MR Research Facility at the Detroit Medical Center. He also was interviewed last week by co-anchor Vargas in New York. The appearance is one of several Rosenberg has made on the program since 2009 about the department’s studies into obsessive compulsive disorder utilizing functional magnetic resonance imaging technology. “I was honored and humbled. Hopefully this is an opportunity to let people know what to recognize, and that there is hope,” he said. He also spoke with ABC’s local affiliate, WXYZ-TV, on May 10 for a related segment about the affects of both regular and excessive iPad use on a person’s behavior and brain. That interview is expected to air at 11 p.m. May 19, following the "20/20" program.