A Wayne State University School of Medicine professor has edited a new book that introducing immunological aspects of pregnancy complications.

“Reproductive Immunology: Basic Concepts,” edited by Gil Mor, M.D., Ph.D., director of the C.S. Mott Center for Human Growth and Development and John M. Malone Jr., M.D., Endowed Professor of Obstetrics and Gynecology, is now available. Dr. More is also interim chair of the Department of Physiology.

Published by Academic Press, the 446-page book offers holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. The book covers topics such as B cells, macrophages and T cells; discussions on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells and the role of fetal Hofbauer cells; the immune regulatory role of glucorticoids; and other topics in the field of reproductive immunology.

The book includes a detailed evaluation of the knowledge of each immune cell type in the uterus, evaluates each immune cell type and its function during specific reproductive events and provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series.