The 20th Aline U. and James M. Orten Memorial Lecture, set for Oct. 15, will feature the principal investigator of the Systems Biology Research Group of the Department of Bioengineering at the University of California, San Diego.
Bernhard Palsson, Ph.D., the Galletti Professor of Bioengineering and professor of Pediatrics for UCSD, will present "Systems Biology of Metabolism" for the 2015 Orten Lecture.
The lecture, presented by the Wayne State University Department of Biochemistry and Molecular Biology, will take place from noon to 2 p.m. in the Green Lecture Hall in Scott Hall.
In his lecture Dr. Palsson will put the field of molecular systems biology into a historical context, review the workflows and procedures that have been developed over the past decade for network reconstruction and go through a series of examples that show how mechanistic metabolic genotype-phenotype relationships are utilized.
Dr. Palsson received his doctoral degree in chemical engineering from the University of Wisconsin-Madison in 1984. Upon graduation, he joined the Chemical Engineering faculty at the University of Michigan, where he was named the G.G. Brown Professor in 1989. In 1995, he joined the Department of Bioengineering at the University of California, San Diego.
His research includes the development of methods to analyze metabolic dynamics (flux-balance analysis, and modal analysis), and the formulation of complete models of selected cells (the red blood cell, E. coli, CHO cells and several human pathogens). Using these models, he can study variations in the genotype and shifts in metabolic routing resulting from changing growth conditions, adaptive evolution or genetic deletions.
Dr. Palsson has co-written more than 400 peer-reviewed research articles and has written five textbooks. He holds more than 40 U.S. patents and is the co-founder of several biotechnology companies. He is a member of the National Academy of Engineering and a fellow of both the American Association for the Advancement of Science and the American Academy of Microbiology.