The National Institutes of Health (NIH) has issued a Request for Information seeking comment on NIH's support of the biomedical and behavioral research processes with the goal of examining the current system to optimize its efficiency and effectiveness. According to the request, the NIH "is especially interested in creative suggestions, even if they involve radical changes to the current approach." Comments will be accepted through Aug. 17. For more information, please visit http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-074.html.